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The series is stated in the current share scale after splits; dividends are not included in the price
| Date | Open | High | Low | Close | Volume, shares |
|---|---|---|---|---|---|
| September 16, 2026 | 47.38 | 47.59 | 44.66 | 44.84 | 8m |
| September 15, 2026 | 51.37 | 51.37 | 46.72 | 47.25 | 7m |
| September 14, 2026 | 54.88 | 55.50 | 51.31 | 51.44 | 6m |
| September 11, 2026 | 55.94 | 56.16 |
Based on reports through March 31, 2026
Ionis switches off the synthesis of individual proteins with short molecules — the platform an entire field grew out of.
The company spent decades developing antisense drugs when almost nobody believed in them, and carried the technology through to approved medicines. The principle is the same as RNA interference: not to block a finished protein but to stop the cell from making it.
For a long time the company lived on licensing: it advanced a programme to a certain stage and handed it to large pharmaceutical partners for royalties. It is now launching drugs itself, which promises a larger share of success and demands a sales force of its own. Risks: trial outcomes, the cost of launching alone and competition from related technologies. The company pays no dividend.
Address:2855 GAZELLE COURT, CARLSBAD, CA, 92010, US
| 1.1bn |
| PFEPfizer, Inc. | 27.64 | +0.66 % | 949m |
| ABTAbbott Laboratories | 102.23 | −0.13 % | 833m |
| VRTXVertex Pharmaceuticals Incorporated | 516.34 | +0.60 % | 553m |
| BMYBristol-Myers Squibb Company | 62.84 | −1.19 % | 539m |
| 54.16 |
| 54.21 |
| 2m |
| September 10, 2026 | 55.75 | 55.77 | 54.91 | 55.65 | 3m |
| September 09, 2026 | 56.38 | 56.96 | 55.70 | 56.02 | 3m |
| September 08, 2026 | 52.15 | 57.43 | 52.15 | 56.71 | 9m |
| September 04, 2026 | 58.36 | 58.96 | 57.78 | 58.09 | 3m |
| September 03, 2026 | 60.42 | 60.42 | 57.47 | 58.13 | 4m |
| September 02, 2026 | 60.25 | 61.77 | 59.78 | 61.33 | 2m |
| September 01, 2026 | 60.37 | 60.99 | 59.78 | 59.88 | 2m |
| August 31, 2026 | 61.07 | 61.07 | 59.70 | 60.36 | 2m |
| August 28, 2026 | 60.62 | 61.69 | 60.35 | 61.05 | 2m |
| August 27, 2026 | 63.48 | 63.48 | 62.34 | 62.43 | 2m |
| August 26, 2026 | 63.50 | 63.55 | 62.44 | 63.36 | 2m |
| August 25, 2026 | 62.53 | 64.19 | 62.19 | 63.57 | 2m |
| August 24, 2026 | 60.54 | 62.07 | 59.70 | 62.04 | 2m |
| August 21, 2026 | 59.64 | 60.92 | 59.06 | 59.74 | 3m |
| August 20, 2026 | 60.03 | 60.41 | 58.60 | 58.76 | 2m |
| August 19, 2026 | 60.11 | 61.36 | 59.61 | 60.80 | 3m |